Bryan Yamamoto is chair of the Department of Pharmacology and Toxicology at the IU School of Medicine. His research focuses on how drugs of abuse affect the neurochemistry of the brain.
Yamamoto has studied how amphetamines, alcohol and their interaction with stress alter brain function and produce damage to regions of the brain that are critically involved in controlling movement and cognition. He is interested in how oxidative, mitochondrial, inflammatory and excitatory processes converge to damage the dopamine and serotonin systems in the brain and how antagonism of these processes mitigates their neurodegenerative effects.
Areas of Expertise
Drugs of abuse and neurodegeneration.